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Scientist, Cell Line Development & Tissue Engineering - Orbillion Bio

Company: Polaris Talent Inc.
Location: Pasadena
Posted on: April 2, 2021

Job Description:

Scientist, Cell Line Development & Tissue Engineering - Orbillion Bio Orbillion Bio is an early stage cultivated meat biotech startup looking for a Scientist in Cell Line Development at thier Pasadena, CA location. Driven by concerns around sustainability and animal welfare, we are developing cultivated meat technology for a healthy and ethical future of food. The founding team brings years of expertise from biopharma, synthetic biology and chemical engineering industries to the table. If you want to help pioneer a new scientific field, are thriving in finding solutions, and would like to work with a fun and innovative team - this is for you! About The Role: Orbillion Bio is looking to hire an (Associate) Scientist to join their rapidly growing R&D team in the cellular agriculture field. This role is seeking an entry to mid-professional with a proven track record in cell biology, cell culture, microscopy, and flow cytometry. A successful candidate will possess an M.S. or PhD with experience in the described skill sets, be able to work independently with minimal supervision, pivot research goals according to the company's interests, and successfully reach milestones according to timelines. You have the unique opportunity to be part of Orbillion Bio R&D for cultivated meat. In this role you will conduct and establish our cell line platforms by applying cutting edge biotechnology to mammalian cell culture and engineering in order to produce commercially relevant cell lines. Required Skills and Experience

  • Strong expertise in mammalian cell culture techniques and derivation of primary and ESC cells.
  • Strong background in cell biology topics including cell cycle, proliferation, differentiation, and cellular adhesion
  • Proficient in sterile aseptic handling of mammalian cells
  • Hands-on experience using CRISPR/Cas9 to edit eukaryotic genomes.
  • Demonstrated ability to optimize genetic engineering protocols to increase efficiency, reduce turnaround time or reduce cost
  • Solid background in molecular biology techniques
  • Experience with cell staining and analysis using flow cytometry and fluorescence microscopy
  • Growth mindset, curiosity, and ability to learn quickly and work independently as a self-directed problem solver
  • Desire to work as a team player and build a diverse, collaborative, and kind work environment
  • Strong organizational skills to prioritize and deliver against timelines and competing priorities
  • Strong verbal and written communication skills
  • A positive attitude that embraces the challenges and opportunities of a dynamic and multidisciplinary startup environment
  • Authorization to work in the US Key Responsibilities
    • Establishing mammalian and avian cell line platforms, including isolation of stem cells and primary cells from tissues and inducing differentiation
    • Ability to maintain mammalian cell culture including isolation, expansion, and cryopreservation of cells
    • Engineering innovative cell manipulations within a food technology context and mindset
    • Designing and validating cellular and molecular quality control markers and pilot scale-up parameters towards cultivated meat production
    • Analyze and present data to a multidisciplinary research team and communicate recommendations and ideas for future research efficiently
    • Conduct literature searches in relevant scientific journals to optimize scientific approaches
    • Communicate project status effectively with team members
    • Analyze and report data in scientific meetings
    • Detailed record keeping of daily scientific activities
    • Independently manage complex projects and junior scientists and RAs Education Requirements
      • PhD in Cell Biology, Bioengineering, Biophysics, Molecular Biology, Biochemistry, or related engineering or life science discipline or 4+ years of relevant industry experience with a Master's degree, or 6+ years with a BS Nice to have skills
        • Experience working with high-throughput screening and lab automation
        • Background in the regulation of gene expression in eukaryotic cells
        • Competency in immunohistochemistry, microscopy and flow cytometry to characterize complex cell phenotypes
        • Experience with 3D culture, microcarriers and/or cell bioreactors (small or large scale)
        • Previous experience in synthetic biology design of novel organisms or cell control systems
        • Advanced bioinformatics and sequencing data analysis skills
        • Basic scripting in relevant languages such as Python, R, SQL, etc.
        • Advanced statistical skills in data analysis using software packages such as R or JMP
        • Experience in DoE and other engineering type experimental design strategies
        • Experience managing RAs and scientists
        • Postdoc experience
        • Experience in flow cytometry and microscopy
        • BSL-1 and BSL-2 Training About Polaris Talent -- Polaris Talent Inc. is a recruiting process outsourcing (RPO) company providing talent acquisition (TA) and human resource (HR) advising for early stage companies to IPO-ready companies who do not have an internal recruiting function or who need to augment their existing team. As an extension of our clients, we evangelize their culture and brand to attract top talent for their open roles and deliver pre-qualified people ready to start the interview process while helping create a robust and scalable internal recruiting operation. We are committed to helping companies hire in a diverse and inclusive way that best serves our communities. Polaris Talent provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Keywords: Polaris Talent Inc., Pasadena , Scientist, Cell Line Development & Tissue Engineering - Orbillion Bio, Engineering , Pasadena, California

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