Associate Scientist - Gene Therapy Research Pasadena
Company: CSL Behring
Location: Pasadena
Posted on: April 6, 2021
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Job Description:
With operations in 35+ nations and - 27,000 employees worldwide,
CSL is driven to develop and deliver a broad range of lifesaving
therapies to treat disorders such as hemophilia and primary immune
deficiencies, and vaccines to prevent influenza. Our therapies are
also used in cardiac surgery, organ transplantation and burn
treatment.CSL is the parent company of CSL Behring and Seqirus. CSL
Behring is a global leader in the protein biotherapeutics industry,
focused on bringing to market biotherapies used to treat serious
and often rare conditions. CSL Behring operates CSL Plasma , one of
the world's largest collectors of human plasma, which is used to
create CSL's therapies. Seqirus is the second largest influenza
vaccine company in the world and is a transcontinental partner in
pandemic preparedness and a major contributor to the prevention and
control of influenza globally.We invite you to take a look at the
many career possibilities available around the globe and consider
building your promising future at CSL by becoming a member of our
team!Position Overview CSL Behring is seeking a highly skilled and
motivated Research Associate/Associate Scientist to join our
growing team. If you want to challenge yourself, accelerate your
career, and give new hope to patients, there's no better place than
here with our Gene Therapy Research team. Full of dedicated team
members, the Gene Therapy Research team is transforming patients'
lives through science. We are looking for an experienced junior
scientist to help us to execute our gene therapy and gene editing
programs. The primary responsibility for this position will be to
assist with in vitro experiments in primary cells and cell lines as
well as in vivo assays focused on the development of gene editing
therapies. The candidate will be involved in the design, execution,
and interpretation of experiments, and will interface regularly
with our internal collaboration partners. From studying
individualized cell lines to making brand new discoveries, this
bold and personal discipline allows you to grow your career while
making a lasting impact on the field of medicine. Join us
today.Responsibilities:* Supporting the implementation,
optimization, and development of novel viral and non-viral gene
therapy approaches* Performing standard molecular biology
techniques, including nucleic acid extraction and PCR* Optimizing
molecular biology detection and quantification techniques, such as
Western blots, ddPCR, ELISA* Planning and conducting CRISPR/Cas9
screens in vitro* Planning and conducting AAV/lentiviral screens in
vitro* Tracking and compiling results in an electronic notebook*
Executing, analyzing, reporting, and documenting data from
experiments in a timely manner* Preparing and presenting data at
cross-functional meetings* Pursuing cross-training opportunities
and learning new technologies as needed to fulfill role* Training
on and following internal policies and procedures to maintain
day-to-day lab operations, quality standards, and training
documentation* Helping to build and promote a positive culture and
working environmentDesired skills* Technical knowledge and hands-on
experience with molecular assays for DNA/RNA quantification and
characterization is preferred (e.g. ddPCR, qPCR, qRT-PCR)*
Experience working with CRISPR/Cas9 and/or AAV/lentiviral gene
delivery is preferred* Experience with transfecting mammalian cells
using technologies such as electroporation or lipid- and
polymer-based particles is desirable* Proficiency with sample
preparation for next-generation sequencing* Experience with
assessment of human peripheral blood stem cells by multicolor flow
cytometry or fluorescent imaging* Experience with hematologic
diseases, liver diseases, primary immunodeficiencies* Collaborative
nature and flexibility to pitch in and help team members to deliver
on commitmentsQualifications:* BS or MS degree in molecular biology
or relevant discipline* BS with 3 years' relevant experience or MS
with 2 years' experience in a molecular biology setting. Additional
prior industry experience preferred* Proficiency and hands-on
experience with primary cell culture is required* Ability to plan,
execute, analyze, critically interpret data, and effectively
multi-task are critical* Strong organizational skills, effective
written and oral communication of scientific data, and good
teamwork are essentialWorker Type:EmployeeWorker Sub
Type:Regular
Keywords: CSL Behring, Pasadena , Associate Scientist - Gene Therapy Research Pasadena, Healthcare , Pasadena, California
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