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Associate Scientist, Tox/Pre-Clinical

Company: CSL Behring
Location: Pasadena
Posted on: July 12, 2019

Job Description:

The Associate Scientist, Preclinical/Toxicology will provide technical support for cellular assays and molecular PCR assays as part of the team supporting GSP and GxP assay execution for pilot studies and vector titration assays. The successful candidate will process patient blood samples and PCR assays for clinical studies. Experience required with GxP testing experience in a regulatory environment and substantial QC experience and documentation skills. Responsibilities: - Carry out flow cytometry, qPCR and RT-qPCR assays to evaluate the efficiency and toxicity of gene delivery and gene editing - Support knock-out or knock-in cell line development activities with gene editing techniques. - Present experimental data at departmental or project team meetings. - Work as part of a team and independently, perform experimental work and report results. - Draft Research Protocols or Standard Operating Procedures (SOP) for the production of gene delivery vectors or generation of cell lines for approval by Scientist and/or Senior Scientist and QA. - Perform routine maintenance of scientific instrumentation, as required. - Ensure critical instruments are calibrated and calibration records maintained. - Ensure that high safety standards are taken into account and adhered to as governed by local, state and federal regulations, laws and policies as well as CSLs policies and directives. - Ordering of reagents and materials Essential Qualifications/Experience: - BS/MS degree in Life Sciences (Cellular Biology/Molecular Biology), Chemistry, Bioengineering, Chemical engineering or related discipline. - Minimum two years hands-on experience with cellular assays/molecular PCR assays - GXP experience - Experience with mammalian cell culture and molecular biology techniques and understanding of gene delivery and gene editing is preferred. Worker Type:Employee Worker Sub Type:Regular

Keywords: CSL Behring, Pasadena , Associate Scientist, Tox/Pre-Clinical, Healthcare , Pasadena, California

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