Senior Scientist, In Vivo Pharmacology, Inflammation Research (Respiratory Focus)

Company: Amgen
Location: Thousand Oaks
Posted on: March 29, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. SeniorScientist, In Vivo Pharmacology, Inflammation Research(Respiratory Focus) What you will do Lets do this. Lets change the world. In this vital role you will leada highly dynamic in vivo pharmacology teamexecutingin vivo preclinical disease models and in vitro assays in the vivarium and lab supporting pipeline programsmanaging interactions and presentation of results with project teams and collaborators. Key Responsibilities: Lead and perform hands-on in vivo work and run concurrent studies mice/possibly rats Serve as manager with at least two direct reports Scientist and Associate Scientists Design experiments, oversee study execution, and ensure studies are completed on scheduled Act as in vivo PTR on project teams: represent and communicate in vivo data to project teams and department Mentor, support, and manage direct reports performance, development, supervision Maintain organization, attention to detail, and study preparation Participate in panels/seminars as part of interview/hiring and in broader scientific communication as needed Participate in weekend/evenings dosing rotations when required. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Senior Scientist we seek is a driven, pro-active, independent, and enthusiastic scientist who wants to contribute tocutting edgescience and serve patients in a highly productive team environment, with strong understanding of Immunology and Inflammation biology and principles. Basic Qualifications: Doctorate degree PhD OR PharmD OR MD and Immunology experience OR Masters degree and 3 years of f Immunology or related experience OR Bachelors degree and 5 years of f Immunology or related experience Preferred Qualifications: Willingness and curiosity to learn and explore new areas of research Significant experienceexecuting in vivo preclinical respiratory disease models,includingasthma (OVA, HDM), COPD (Elastase, smoke extract), Bleomycin fibrosis (i.t.,i.d.,s.c.), respiratory virus infection (PR8) Experience with preclinical inflammatory disease models, including colitis, lupus, RA, PBC important Significant hands-onexpertisein animal (mouse and rat) handling and in vivo techniques (i.v.,i.p.,p.o.,i.d.,s.c., i.t., bleeds, necropsy) SignificantExperience with lung function measurements (FlexiVent, Plethysmography),imaging (mCT), and inhaled drug delivery Hands-on experience in cellular, biochemical, histological, and molecular biology assay techniques (i.e.ELISA, MSD, quantitative RT-PCR, BCA protein measurements) Hands-on experience with multicolor flow cytometry including Spectral flow approaches and Immune cell populations is essential Computer literacy, especiallyproficiencywith GraphPad Prism, Excel,PowerPointand Word Attention to detail, excellent organizational and communication skills,accurate& timelyrecordkeepingand data analysis are essential. Demonstratedtrack recordof independent critical thinking and scientific achievement. Demonstrated experience in andunderstandof pharmacology with applicationusing invivo models of inflammation/Immunology Experience working on project teams leading in vivo contributions Experience managing an in vivo pharmacology team or direct reports (2 years) Ability to work in aflexibleteam-oriented environment.Weekend and evening work may berequired. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Keywords: Amgen, Pasadena , Senior Scientist, In Vivo Pharmacology, Inflammation Research (Respiratory Focus), Science, Research & Development , Thousand Oaks, California